26, P?=?0.06). Programmes Sitaxentan
of longer duration had significantly lower attendance rates (r?=??0.42, P?=?0.002), although the percentage of variance in attendance explained by programme duration was low (r2?<?20%). Twenty studies (23%) involving 33 active intervention groups reported both prescribed and attended supervised sessions (training volume; frequency of supervised exercise per week?��?programme duration) and data which enabled improvement in exercise outcomes to be calculated as a percentage change from baseline (rather than metres).[11, 13-15, 20, 28-30, 36, 44, 45, 53, 54, 57, 59, 65, 66, 68, 69, 72] Seventeen studies used the 6?min walk test, one study used the 12?min walk test and two studies used the incremental shuttle walk test.[36, 65] Risk of methodological bias was moderate across studies (median score 6/10, range 2�C8, where scores approaching 10 indicate low risk of methodological bias) (Supplementary Information Table S3). On average, the difference between the prescribed maximum number of supervised exercise sessions and the mean number of exercise <a href="http://www.selleckchem.com/screening/anti-cancer-compound-library.html
">Anti-cancer Compound Library sessions attended was 3 (��?5) (range +6 to ?19; prescribed training volume?=?25?��?8 vs attended training volume?=?22?��?6). This equates to a mean of 7% of prescribed exercise sessions not being attended. There was little to no relationship (r?=?0�C0.25) between improvements in functional exercise capacity and training volume (prescribed r?=??0.03, P?=?0.88 or attended r?=??0.24, P?=?0.18 Fig.?3). Improvements in exercise outcomes ranged from a mean increase of 8% (mean number of sessions attended 30% greater than the maximum number of sessions prescribed) to a mean increase of 15% in exercise outcome (mean number of sessions attended 52% lower than the maximum number of session's prescribed). This review clearly demonstrates low levels of reporting attendance data with a wide variety of metrics described in published trials of exercise training programmes for people with COPD. After reviewing 234 eligible full-text articles, only 37% reported attendance of participants in exercise training Alectinib supplier
sessions, and of these, 12% reported a priori criteria for attendance (range 50 and 100%). Fair associations were calculated between exercise session attendance, exercise frequency and programme duration. No significant association was found between improvements in exercise performance and prescribed or attended training volume. It is important to note that our analysis included only those studies published in English that reported attendance rates at supervised exercise training sessions. On review of a random sample (15%) of studies excluded due to the language of publication, it appears unlikely that inclusion of studies published in a language other than English would have improved the reporting rate for attendance.